Biodynamic activities of ellagic acid: A dietary polyphenol
نویسندگان
چکیده
منابع مشابه
The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.
Ellagic acid (EA), a polyphenol present in berries, has been demonstrated to be preventive of esophageal and colon cancer in animals. Here, we have studied the ability of organic anion transporters (OATs) and organic anion-transporting polypeptides (OATPs) to transport EA. The accumulation of radiolabeled (14)C]EA, [(3)H]p-aminohippuric acid (PAH), [(14)C]glutarate, [(3)H]estrone sulfate, [(3)H...
متن کاملShort Communication THE DIETARY POLYPHENOL ELLAGIC ACID IS A POTENT INHIBITOR OF hOAT1
Ellagic acid (EA), a polyphenol present in berries, has been demonstrated to be preventive of esophageal and colon cancer in animals. Here, we have studied the ability of organic anion transporters (OATs) and organic anion-transporting polypeptides (OATPs) to transport EA. The accumulation of radiolabeled [C]EA, [H]p-aminohippuric acid (PAH), [C]glutarate, [H]estrone sulfate, [H]ochratoxin A, a...
متن کاملShort Communication THE DIETARY POLYPHENOL ELLAGIC ACID IS A POTENT INHIBITOR OF hOAT1
Ellagic acid (EA), a polyphenol present in berries, has been demonstrated to be preventive of esophageal and colon cancer in animals. Here, we have studied the ability of organic anion transporters (OATs) and organic anion-transporting polypeptides (OATPs) to transport EA. The accumulation of radiolabeled [C]EA, [H]p-aminohippuric acid (PAH), [C]glutarate, [H]estrone sulfate, [H]ochratoxin A, a...
متن کاملAntioxidant and apoptosis-inducing activities of ellagic acid.
BACKGROUND Antioxidant, antiproliferative and apoptosis inducing activities of a natural polyphenolic compound, ellagic acid, were studied. MATERIALS AND METHODS DPPH radical scavenging and lipid peroxidation inhibitory activities were observed. Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were measured in ellagic acid-treated ...
متن کاملCombined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound.
The vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors play essential and complementary roles in angiogenesis and combined inhibition of these receptors has been shown to result in potent antitumor activity in vivo. In this study, we report that ellagic acid (EA), a natural polyphenol found in fruits and nuts, inhibits VEGF-induced phosphorylation of V...
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ژورنال
عنوان ژورنال: Journal of Nature and Science of Medicine
سال: 2020
ISSN: 2589-627X
DOI: 10.4103/jnsm.jnsm_32_19